Journal: Translational Neuroscience

Article Title: EGCG modulates PKD1 and ferroptosis to promote recovery in ST rats

doi: 10.1515/tnsci-2020-0119

Figure Lengend Snippet: Effect of EGCG on CGNs and functional recovery in rats after complete ST. EGCG increased PKD1 phosphorylation and inhibited ferroptosis to promote functional recovery in rats, as indicated by (a) increased BBB score, (b) knee joint angle, (c) speed in the rotarod test, and (d) biceps femoris muscle weight. (* p < 0.05, ** p < 0.01, *** p < 0.0001, n = 8.)

Article Snippet: The Rotamex Rotarod system (UGO Basile Rat&Mouse Rota-Rod 47700/600, Italy) contained a rotating rod that was divided into five parts by a splitter plate to permit the testing of five animals at one time.

Techniques: Functional Assay, Phospho-proteomics

Journal: PLoS ONE

Article Title: Optimised Motion Tracking for Positron Emission Tomography Studies of Brain Function in Awake Rats

doi: 10.1371/journal.pone.0021727

Figure Lengend Snippet: Diagram showing the six degree-of-freedom robot with the hot rod phantom attached to the end-effector. The apparent location of the end-effector was shifted along the axis of the phantom by 45 mm, corresponding to the middle third of the cylinder. This more closely resembled the proximity of the marker to the brain in the original motion data. The 8-point and 3-point markers used for tracking were stuck to the marker substrate (on the opposite side to that visible here).

Article Snippet: To investigate the impact of the rate of motion and marker size on tracking accuracy, arbitrary movements of differing rates were manually applied to a Micro Deluxe hot rod phantom (Data Spectrum Corporation, NC, USA).

Techniques: Marker

Journal: PLoS ONE

Article Title: Optimised Motion Tracking for Positron Emission Tomography Studies of Brain Function in Awake Rats

doi: 10.1371/journal.pone.0021727

Figure Lengend Snippet: Motion correction of the 20-min hot rod study with slow-moderate manually applied motion (see ). Left to right are orthogonal views of the centre of the phantom. Row 1: no motion correction; row 2: motion free; row 3: correction based on the 8-point marker; row 4: correction based on the 3-point marker. The pose sampling rate during tracking was 30 Hz. Note that the white bars marked on the motion-free image represent the location of profiles shown in .

Article Snippet: To investigate the impact of the rate of motion and marker size on tracking accuracy, arbitrary movements of differing rates were manually applied to a Micro Deluxe hot rod phantom (Data Spectrum Corporation, NC, USA).

Techniques: Marker, Sampling

Journal: PLoS ONE

Article Title: Optimised Motion Tracking for Positron Emission Tomography Studies of Brain Function in Awake Rats

doi: 10.1371/journal.pone.0021727

Figure Lengend Snippet: Motion correction of the 5-min hot rod study with fast manually applied motion (see ). Left to right are orthogonal views through the centre of the phantom. Row 1: no motion correction; row 2: motion free; row 3: correction based on the 8-point marker; row 4: correction based on the 3-point marker. The pose sampling rate during tracking was 30 Hz. Note that the white bars marked on the motion-free image represent the location of profiles shown in .

Article Snippet: To investigate the impact of the rate of motion and marker size on tracking accuracy, arbitrary movements of differing rates were manually applied to a Micro Deluxe hot rod phantom (Data Spectrum Corporation, NC, USA).

Techniques: Marker, Sampling

Journal: PLoS ONE

Article Title: Optimised Motion Tracking for Positron Emission Tomography Studies of Brain Function in Awake Rats

doi: 10.1371/journal.pone.0021727

Figure Lengend Snippet: Comparison of the reconstructed hot rod phantom images with and without motion correction. The top panel shows profiles for the 20-min study with slow-moderate manually applied motion, and the bottom panel shows profiles for the 5 min study with fast manually applied motion. Profiles were drawn through the transverse reconstructed images at the level indicated in and . The pose sampling rate during tracking was 30 Hz.

Article Snippet: To investigate the impact of the rate of motion and marker size on tracking accuracy, arbitrary movements of differing rates were manually applied to a Micro Deluxe hot rod phantom (Data Spectrum Corporation, NC, USA).

Techniques: Comparison, Sampling

Journal: PLoS ONE

Article Title: Optimised Motion Tracking for Positron Emission Tomography Studies of Brain Function in Awake Rats

doi: 10.1371/journal.pone.0021727

Figure Lengend Snippet: Motion correction of the hot rod study with slow-moderate manually applied motion. A 72 s segment of the data has been corrected so that it is comparable (in terms of counting statistics) with the fast motion study. Left to right shows orthogonal views of the centre of the phantom. Correction was based on the 8-point marker measurements. These images can be compared with those in (row 3) in order to see the effect that the rate of motion had on motion correction accuracy.

Article Snippet: To investigate the impact of the rate of motion and marker size on tracking accuracy, arbitrary movements of differing rates were manually applied to a Micro Deluxe hot rod phantom (Data Spectrum Corporation, NC, USA).

Techniques: Marker

Journal: PLoS ONE

Article Title: Optimised Motion Tracking for Positron Emission Tomography Studies of Brain Function in Awake Rats

doi: 10.1371/journal.pone.0021727

Figure Lengend Snippet: Motion correction of the hot rod study corrupted by the robot-generated rat motion. Left to right are orthogonal views of the centre of the phantom. Row 1: no motion correction; row 2: motion free; row 3: correction based on the 8-point marker; row 4: correction based on the 3-point marker. The pose sampling rate during tracking was 30 Hz.

Article Snippet: To investigate the impact of the rate of motion and marker size on tracking accuracy, arbitrary movements of differing rates were manually applied to a Micro Deluxe hot rod phantom (Data Spectrum Corporation, NC, USA).

Techniques: Generated, Marker, Sampling

Journal: PLoS ONE

Article Title: Optimised Motion Tracking for Positron Emission Tomography Studies of Brain Function in Awake Rats

doi: 10.1371/journal.pone.0021727

Figure Lengend Snippet: Examples of motion-corrected hot rod phantom reconstructions obtained with varying degrees of tracker-scanner synchronisation error (top row) and various pose sampling rates (bottom row). Results are shown for a central transverse slice.

Article Snippet: To investigate the impact of the rate of motion and marker size on tracking accuracy, arbitrary movements of differing rates were manually applied to a Micro Deluxe hot rod phantom (Data Spectrum Corporation, NC, USA).

Techniques: Sampling